Hall & Oates, Train To Co-Headline Summer Tour

first_imgThis summer, Daryl Hall and John Oates are teaming up with Train for a co-headlining North American tour. Both bands will perform full sets before joining forces for a third final set. The tour will kick off in May at the Golden One Center in Sacramento, CA and extend through August 11th at the KeyArena in Seattle, WA.“This is going to be a tour filled with fun as well as great music,” Hall explains in a statement. “I love Train and have a close relationship with Pat Monahan, going back to our Live From Daryl’s House show together.” “Looking forward to an amazing tour with our buddies from Train and seeing all our fans around the country in 2018,” Oates adds.“I’ve known Daryl Hall and John Oates for a few years now and after being their fan my entire life, we now get to tour with them and spend time with legends in the world of music,” Monahan expressed in a statement. “This will be a career highlight for all of us in Train and a show that you won’t want to miss.”Tickets to the upcoming Daryl Hall and John Oates and Train tour will go on sale this Friday, January 29th at 10am local time in most cities via Live Nation. Daryl Hall and John Oates and Train Tour Dates5/1 – Sacramento, CA @ Golden 1 – Center5/4 – San Jose, CA @ SAP Center5/6 – Anaheim, CA @ Honda Center5/8 – Salt Lake City, UT @ Vivint Smart Home Arena5/10 – Denver, CO @ Pepsi Center5/12 – St. Louis, MO @ Scottrade Center5/16 – St. Paul, MN @ Xcel Energy Center5/18 – Chicago, IL @ United Center5/20 – Detroit, MI @ Little Caesars Arena5/22 – Cleveland, OH @ Quicken Loans Arena5/24 – Columbus, OH @ Nationwide Arena5/26 – Philadelphia, PA @ HoagieNation Festival6/5 – Toronto, ON @ Air Canada Centre6/7 – Boston, MA @ Xfinity Center6/9 – Pittsburgh, PA @ PPG Paints Arena6/11 – Washington, DC @ Capital One Arena6/14 – New York, NY @ Madison Square Garden6/18 – Charlotte, NC @ Spectrum Center6/20 – Atlanta, GA @ Infinite Energy Center6/22 – Tampa, FL @ Amalie Arena6/24 – Ft. Lauderdale, FL @ BB&T Center6/26 – Orlando, FL @ Amway Center6/28 – New Orleans, LA @ Smoothie King Center6/30 – Nashville, TN @ Bridgestone Arena7/13 – Montreal, QC @ Bell Centre7/15 – Grand Rapids, MI @ Van Andel Arena7/18 – Omaha, NE @ CenturyLink Center7/20 – Kansas City, MO @ Sprint Center7/22 – Oklahoma City, OK @ Chesapeake Energy Arena7/24 – Dallas, TX @ American Airlines Center7/26 – Houston, TX @ Toyota Center7/28 – Austin, TX @ Frank Erwin Center7/31 – Los Angeles, CA @ The Forum8/4 – San Diego, CA @ Viejas Arena8/7 – Oakland, CA @ Oracle Arena8/9 – Portland, OR @ Moda Center8/11 – Seattle, WA @ KeyArena[via Rolling Stone]last_img read more

‘He wanted to prove everybody wrong’: Tony Adams hails Arsenal’s David Luiz for defiant display against Man City

first_imgArteta has led his side to the FA Cup final in his first season (Picture: Getty Images)‘If there was a crowd in the audience, I don’t know if that’s helped him or not, I’m thinking it may have helped him because in recent weeks I think the Arsenal crowd would have been really on his back and I don’t know how he would’ve reacted with that, but he certainly reacted for me so well. ‘For this game in particular I just thought he was awesome and I’m going to be shouting from the top of the world that he was outstanding, good performance.’More: Arsenal FCArsenal flop Denis Suarez delivers verdict on Thomas Partey and Lucas Torreira movesThomas Partey debut? Ian Wright picks his Arsenal starting XI vs Manchester CityArsene Wenger explains why Mikel Arteta is ‘lucky’ to be managing ArsenalSpeaking after the game, Luiz responded to his many critics with a defiant message.‘[There was] a lot of criticism of me, you can say that,’ he told BT Sport.‘It is part of the football, I understood during my career football is about surviving every day you are going to defend your team and other people are going to support their teams it is about surviving.‘It is what I did I was working very hard every day after my mistakes I took the blame I was mature enough to understand that and I was humble to do that for the team.’MORE: Arsenal legend Ian Wright picks out six star performers after sensational Man City winMORE: Robin van Persie picks out ‘absolutely fantastic’ David Luiz as Arsenal stun Man City in FA Cup semi-finalFollow Metro Sport across our social channels, on Facebook, Twitter and Instagram.For more stories like this, check our sport page. Comment Advertisement Metro Sport ReporterSunday 19 Jul 2020 8:22 amShare this article via facebookShare this article via twitterShare this article via messengerShare this with Share this article via emailShare this article via flipboardCopy link1.8kShares ‘He wanted to prove everybody wrong’: Tony Adams hails Arsenal’s David Luiz for defiant display against Man City Luiz showcased the best parts of his game against City (Picture: Getty Images)Tony Adams has heaped praise on the ‘absolutely phenomenal’ performance of David Luiz after Arsenal’s shock 2-0 FA Cup semi-final win against Manchester City.The Gunners churned out a dogged display against City, with captain Pierre-Emerick Aubameyang scoring twice to seal the north London club’s place in the final.Brazilian defender Luiz has come under fire for recent high-profile errors, but was one of Mikel Arteta’s side’s top performers at Wembley on Saturday evening.And Arsenal legend Adams – who admitted earlier this week that he would ‘struggle’ to play alongside the centre-back – singled out Luiz’s resurgent display.AdvertisementAdvertisementADVERTISEMENT‘David Luiz was absolutely phenomenal and I’ve been very critical of him recently and I think a lot of people have been,’ Adams told Stadium Astro.‘So, give credit where credits due, he had the bit between his teeth. He wanted to prove everybody wrong. Advertisementlast_img read more

Researchers discover biomarkers that accurately identify hypervirulent K pneumoniae

first_imgJul 9 2018Imagine a pathogen that infects completely healthy people and can cause blindness in one day and flesh-eating infections, brain abscesses and death in just a few days. Now imagine that this pathogen is also resistant to all antibiotics.This is the nightmare scenario that obsesses Thomas A. Russo, MD, professor of medicine in the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo. Since seeing his first case in Buffalo seven years ago, he has been investigating hypervirulent Klebsiella pneumoniae, a rare but increasingly common strain of K. pneumoniae.There is no accurate method for distinguishing between the hypervirulent strain from the classical strain of K. pneumoniae, which is most often seen in the Western hemisphere, is less virulent and usually causes infections in hospital settings.Now Russo, who heads the Division of Infectious Diseases in the UB Department of Medicine, and his colleagues have discovered several biomarkers that can accurately identify hypervirulent K. pneumoniae. The research was published in late June in the Journal of Clinical Microbiology.In a commentary paper the journal published on June 27, authors from the Fujita Health University School of Medicine in Japan and the University of Pittsburgh School of Medicine noted that the UB research is “a major step forward” in developing a consensus definition of the hypervirulent strain and in designing international studies to reveal more about its epidemiology and clinical presentation.”Presently, there is no commercially available test to accurately distinguish classical and hypervirulent strains,” said Russo. “This research provides a clear roadmap as to how a company can develop such a test for use in clinical laboratories. It’s sorely needed.”Russo added that a definitive diagnostic test would not only optimize patient care but would also allow researchers to perform epidemiologic surveillance to track how frequently the hypervirulent strain causes infection and how frequently it acquires antimicrobial resistance.While the assumption is that the pathogen spreads from person to person through food and water, the mode of transmission is unknown.No way to tell the differenceRusso explains that both strains of K. pneumoniae can be deadly, but the classical strain is more likely to infect patients with underlying disease, or who are immune-compromised and hospitalized.By contrast, the hypervirulent strain can infect healthy, young people in the community, causing sudden, life-threatening complications, ranging from liver or brain abscesses to flesh-eating infections. While it’s currently less likely to be antibiotic resistant, these strains continue to evolve. Classical strains are more likely to be antimicrobial resistant.”What’s increasingly concerning is the growing number of reports that describe strains of hypervirulent K. pneumoniae that are antimicrobial resistant,” said Russo. “A bug that’s both hypervirulent and challenging to treat is a bad combination.”Related StoriesStudy offers clues about how to prevent brain inflammation in Alzheimer’sStudy provides new insight into longitudinal decline in brain network integrity associated with agingNew research links “broken heart syndrome” to cancerAn antimicrobial-resistant hypervirulent strain can develop in one of two ways, he explained: either by acquiring antimicrobial-resistance genes, or when an antimicrobial-resistant classical strain acquires hypervirulence.”The latter mechanism is what caused the deaths of five patients in the intensive care unit of a hospital in Hangzhou, China, which was reported early this year,” Russo said.Since clinical laboratories have no test to detect the hypervirulent strain, it’s difficult, if not impossible, to properly diagnose it. The so-called string test, currently used in some cases to distinguish the classical and hypervirulent strains, is not consistently accurate, according to the UB research. It’s especially problematic, Russo said, in North America and Europe, where there is a low prevalence of the hypervirulent strain.”Many clinicians are unaware of the hypervirulent strain,” said Russo. “And because there’s no diagnostic test, the clinical lab can’t give them a heads up.”Finding the source of hypervirulenceRusso and his co-authors knew that the hypervirulence of K. pneumoniae is largely due to genes located on a large virulence plasmid, DNA that is independent from the chromosome. They hypothesized that some of these genes, including those producing iron-acqusition molecules called siderophores, might be good biomarkers. This proved to be the case.They also found that higher concentrations of siderophores predicted hypervirulence. They then validated the identified biomarkers in a mouse infection model.”The advantage of identifying these genetic biomarkers is that they can be developed into rapid nucleic acid tests, and if approved by the Food and Drug Administration, would then provide clinicians with an accurate method to quickly determine if a patient is suffering from an infection due to the classical or hypervirulent strain,” Russo explained.He added that such a test will not only benefit patients and possibly save lives, but will also prove critical in learning more about hypervirulent K. pneumoniae.”For example, we don’t know the frequency of infection by hypervirulent K. pneumoniae in different parts of the world,” he said. “We know it infects all ethnic groups, but so far it’s been described most often in Asians, particularly in Asian Pacific Rim countries. Is that because hypervirulent K. pneumoniae is more commonly acquired in that part of the world but doesn’t necessarily result in infection, or because some Asian populations are, for some reason, more susceptible to it? Now we can begin to study those kinds of epidemiological questions.”Source: http://www.buffalo.edu/news/releases/2018/07/001.htmllast_img read more